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Committee Detail

Note: An Annual Comprehensive Review, as required by §7 of the Federal Advisory Committee Act, is conducted each year on committee data entered for the previous fiscal year (referred to as the reporting year). The data for the reporting year is not considered verified until this review is complete and the data is moved to history for an agency/department. See the Data From Previous Years section at the bottom of this page for the committee’s historical, verified data.


HHS - 113 - National Toxicology Program Board of Scientific Counselors - Authorized by Law
Hide Section - GENERAL INFORMATION

GENERAL INFORMATION

Committee NameNational Toxicology Program Board of Scientific CounselorsAgency NameDepartment of Health and Human Services
Fiscal Year2020Committee Number113
Original Establishment Date11/15/1978Committee StatusChartered
Actual Termination Date Committee URLhttps://ntp.niehs.nih.gov/whoweare/advisory/ind...
New Committee This FYNoPresidential Appointments*No
Terminated This FYNoMax Number of Members*20
Current Charter Date11/14/2020Designated Fed Officer Position Title*DIRECTOR, NTP OFFICE OF LIAISON, POLICY AND REVIEW
Date Of Renewal Charter11/14/2022Designated Federal Officer Prefix
Projected Termination Date Designated Federal Officer First Name*MARY
Exempt From Renewal*NoDesignated Federal Officer Middle Name
Specific Termination AuthorityDesignated Federal Officer Last Name*WOLFE
Establishment Authority*Authorized by LawDesignated Federal Officer SuffixPHD
Specific Establishment Authority*42 U.S.C. 217aDesignated Federal Officer Phone*919-541-7539
Effective Date Of Authority*11/17/1962Designated Federal Officer Fax*919-541-0295
Exempt From EO 13875 Discretionary CmteExempt: Merit Review PanelDesignated Federal Officer Email*wolfe@niehs.nih.gov
Committee Type*Continuing
Presidential*No
Committee Function*Other Committee
Hide Section - RECOMMENDATION/JUSTIFICATIONS

RECOMMENDATION/JUSTIFICATIONS

Agency Recommendation*Continue
Legislation to Terminate RequiredNot Applicable
Legislation StatusNot Applicable
How does cmte accomplish its purpose?*The National Toxicology Program (NTP) Board of Scientific Counselors (BSC) is a technical advisory body established to advise the NTP Executive Committee and NTP Director on matters relating to scientific program content and to evaluate the scientific merits of the intramural and collaborative programs of the NTP. The BSC typically meets twice annually and convenes working groups and subcommittees to address special programmatic issues as needed. Meetings are open to the public and webcast, written comments were received, and time was provided at the meeting for oral public comment. Information about BSC meetings can be found at http://ntp.niehs.nih.gov/go/164.
How is membership balanced?*Members of the BSC are selected from recognized authorities knowledgeable in fields such as toxicology, pharmacology, pathology, biochemistry, epidemiology, mutagenesis, immunology, carcinogenesis, industrial hygiene, reproductive toxicology, and biostatistics. The Secretary, Health and Human Services, appoints members to the BSC. The members review the NTP activities in the above areas and provide scientific oversight to the program.
How frequent & relevant are cmte mtgs?*The BSC typically meets twice each fiscal year and convenes working groups and subcommittees to address special programmatic issues. Continuation of the BSC is necessary because there is no other available source that can provide a proper blend of programmatic review and advice needed by the NTP. The BSC met once this fiscal year.
Why advice can't be obtained elsewhere?*Because of the unique function and objectives of the NTP within the public sector, an independent advisory board is required that includes a breadth of scientific expertise within the membership and a membership that can evaluate and advise on activities ranging from basic research to actual large-scale chemical testing.
Why close or partially close meetings?N/A
Recommendation RemarksCommittee Function - Other, Scientific and Technical Peer Review.

Based on the assignment of duties within the National Toxicology Program, the designated federal official (DFO) and committee decision maker positions are held by the same individual.

Reports: This committee did not produce any reports during this fiscal year.

Members: FY20 retirees, Paul Brandt-Rauf, Myrtle Davis, Jennifer Sass, and Donald Stump were administratively extended as per the Charter. FY19 retirees, Kass, Barlow, McMartin, Ramos, Stevens, and Waters were administratively extended as well and are, therefore, included in the FY20 report. Kenneth McMartin was the Chair, until 12/2019 and David Eaton is currently the "Acting" Chair. He will be officially reassigned once the 2020 nomination slate is approved.
Hide Section - PERFORMANCE MEASURES

PERFORMANCE MEASURES

Outcome Improvement To Health Or Safety*YesAction Reorganize Priorities*No
Outcome Trust In GovernmentYesAction Reallocate ResourcesNo
Outcome Major Policy ChangesNoAction Issued New RegulationsNo
Outcome Advance In Scientific ResearchYesAction Proposed LegislationNo
Outcome Effective Grant MakingNoAction Approved Grants Or Other PaymentsNo
Outcome Improved Service DeliveryYesAction OtherYes
Outcome Increased Customer SatisfactionYesAction CommentThe Committee makes recommendations to federal staff. The National Toxicology Program (NTP) Board of Scientific Counselors (BSC) advises the NTP Executive Committee and NTP Director on matters relating to scientific program content and to evaluate the scientific merits of the intramural and collaborative programs of the NTP.
Outcome Implement Laws/Reg RequirementsNoGrants Review*No
Outcome OtherNoNumber Of Grants Reviewed0
Outcome CommentNANumber Of Grants Recommended0
Cost Savings*NoneDollar Value Of Grants Recommended$0.00
Cost Savings CommentNIH supported basic and clinical research accomplishments often take many years to unfold into new diagnostic tests and new ways to treat and prevent diseases.Grants Review CommentAlthough grant reviews are included in the duties of this Board, there were no grant reviews performed during this fiscal year.
Number Of Recommendations*193Access Contact Designated Fed. Officer*Yes
Number Of Recommendations CommentThe BSC meeting was held on February 21, 2020, via webcast, to review and provide scientific input on the NTP’s activities and collaborative programs. Agenda topics included discussions and presentations on:

1. Evolving the Paradigm: In Vivo to In Vitro Extrapolation, Microphysiological Systems-Enabled “Virtual Human” Hazard Assessment: A Concept. The BSC heard how microphysiological systems offer an opportunity to get closer to the complexity of in vivo systems to potentially re-invent how toxicology is done.

2. Understanding Human Exposure to Nanoparticles/Microplastics: Novel Agents Bring Novel Challenges. The board was briefed on recent developments in research on human exposure to nanoplastics and microplastics, including the global challenge represented by plastic waste, and provided an update on activities by national and international regulatory agencies addressing the problem.

3. Hypertensive Disorders of Pregnancy and Environmental Exposures: Disease as a Toxicology Focus. The board was briefed on recent work related to hypertensive disorders of pregnancy (HDP) and environmental exposures. Based on the NTP nomination to evaluate emerging health issues associated with ambient air pollution, HDP were identified as an emerging air pollution-related health issue affecting mother and child. HDP affect up to 10% of pregnancies worldwide and are a leading cause of maternal and fetal mortality and morbidity. Preeclampsia is the most common form of hypertension during pregnancy and causes 60,000+ maternal deaths and 500,000 fetal deaths each year.

4. NTP Studies of Per- and Poly-fluoroalkyl Substances: Understanding Human Translation. The BSC was briefed on NTP studies of per and poly-fluoroalkyl substances (PFAS). Among the multiple chemicals within the PFAS class, manufacturers have agreed to discontinue the use of perfluorooctanoic acid (PFOA) and perfluorooctanesulfonic acid (PFOS) due to widespread exposure and health concerns. While exposure has declined for some PFAS, newer PFAS have been identified. PFOA cancer assessments were undertaken in 2016 by the International Agency for Research on Cancer and the U.S. Environmental Protection Agency (EPA).

The BSC had 5 recommendations concerning PFAS and PFOA with regards to public communications and 2 recommendations for the concept, In Vivo to In Vitro Extrapolation, Microphysiological Systems-Enabled “Virtual Human” Hazard Assessment, initiative which included using animal-derived cell systems to make comparisons with the animal studies and collecting pharmacokinetic data that may be relevant.
Access Agency WebsiteNo
% of Recs Fully Implemented*0.00%Access Committee WebsiteYes
% of Recs Fully Implemented CommentDue to the large breadth and complexity of the recommendations made by this committee, staff is unable to determine which recommendations have been fully or partially implemented solely in response to this committee's activities.Access GSA FACA WebsiteYes
% of Recs Partially Implemented*0.00%Access PublicationsNo
% of Recs Partially Implemented CommentNAAccess OtherYes
Agency Feedback*YesAccess CommentNewsletter, List Serve
Agency Feedback Comment*Website and at subsequent meetings.Narrative Description*The National Toxicology Program Board of Scientific Counselors (Board) is a technical advisory body established to advise the National Toxicology Program (NTP) Executive Committee and Program Director on matters relating to the scientific program content and to evaluate the scientific merits of the intramural and collaborative programs of the NTP, and as requested by the Secretary, undertake peer review of extramural funding applications as required by section 492 of the public Health Service Act, as amended.
Hide Section - COSTS

COSTS

Payments to Non-Federal Members*$2,000.00Est Payments to Non-Fed Members Next FY*$21,600.00
Payments to Federal Members*$0.00Est. Payments to Fed Members Next FY*$0.00
Payments to Federal Staff*$102,390.00Estimated Payments to Federal Staff*$105,053.00
Payments to Consultants*$0.00Est. Payments to Consultants Next FY*$0.00
Travel Reimb. For Non-Federal Members*$0.00Est Travel Reimb Non-Fed Members nextFY*$7,424.00
Travel Reimb. For Federal Members*$0.00Est Travel Reimb For Fed Members*$0.00
Travel Reimb. For Federal Staff*$0.00Est. Travel Reimb to Fed Staff Next FY*$0.00
Travel Reimb. For Consultants*$0.00Est Travel Reimb to Consultants Next FY*$0.00
Other Costs$14,140.00Est. Other Costs Next FY*$14,423.00
Total Costs$118,530.00Est. Total Next FY*$148,500.00
Federal Staff Support (FTE)*0.70Est. Fed Staff Support Next FY*0.70
Cost RemarksCosts are lower than last year due to fewer meetings.Est Cost Remarks
Hide Section - Interest Areas

Interest Areas

Category
Area
Medicine
Health and Health Research
Hide Section - MEMBERS,MEETINGS AND ADVISORY REPORTS

MEMBERS,MEETINGS AND ADVISORY REPORTS

To View all the members, meetings and advisory reports for this committee please click here
Hide Section - CHARTERS AND RELATED DOCS

CHARTERS AND RELATED DOCS

No Documents Found
Hide Section - DATA FROM PREVIOUS YEARS

DATA FROM PREVIOUS YEARS

Committee

Data from Previous Years

 
ActionCommittee System IDCommittee NameFiscal Year
 COM-036424National Toxicology Program Board of Scientific Counselors2019
 COM-034630National Toxicology Program Board of Scientific Counselors2018
 COM-001866National Toxicology Program Board of Scientific Counselors2017
 COM-002580National Toxicology Program Board of Scientific Counselors2016
 COM-003806National Toxicology Program Board of Scientific Counselors2015
 COM-004369National Toxicology Program Board of Scientific Counselors2014
 COM-006183National Toxicology Program Board of Scientific Counselors2013
 COM-006837National Toxicology Program Board of Scientific Counselors2012
 COM-008295National Toxicology Program Board of Scientific Counselors2011
 COM-009110National Toxicology Program Board of Scientific Counselors2010
 COM-010058National Toxicology Program Board of Scientific Counselors2009
 COM-010958National Toxicology Program Board of Scientific Counselors2008
 COM-012157National Toxicology Program Board of Scientific Counselors2007
 COM-012499National Toxicology Program Board of Scientific Counselors2006
 COM-013977National Toxicology Program Board of Scientific Counselors2005
 COM-014513National Toxicology Program Board of Scientific Counselors2004
 COM-015993National Toxicology Program Board of Scientific Counselors2003
 COM-016402National Toxicology Program Board of Scientific Counselors2002
 COM-017819National Toxicology Program Board of Scientific Counselors2001
 COM-018588National Toxicology Program Board of Scientific Counselors2000
 COM-019855National Toxicology Program Board of Scientific Counselors1999
 COM-020613National Toxicology Program Board of Scientific Counselors1998
 COM-021463National Toxicology Program Board of Scientific Counselors1997